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» Reconstructing the Topology of Protein Complexes
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78
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BMCBI
2007
168views more  BMCBI 2007»
14 years 10 months ago
Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks
Background: Uncovering cellular roles of a protein is a task of tremendous importance and complexity that requires dedicated experimental work as well as often sophisticated data ...
Nikolai Daraselia, Anton Yuryev, Sergei Egorov, Il...
78
Voted
SODA
2008
ACM
104views Algorithms» more  SODA 2008»
14 years 11 months ago
Fast and reliable reconstruction of phylogenetic trees with very short edges
Abstract Ilan Gronau Shlomo Moran Sagi Snir Phylogenetic reconstruction is the problem of reconstructing an evolutionary tree from sequences corresponding to leaves of that tree. ...
Ilan Gronau, Shlomo Moran, Sagi Snir
BMCBI
2010
160views more  BMCBI 2010»
14 years 10 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
110
Voted
BMCBI
2007
227views more  BMCBI 2007»
14 years 10 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
74
Voted
COMPGEOM
2010
ACM
15 years 3 months ago
Optimal reconstruction might be hard
Sampling conditions for recovering the homology of a set using topological persistence are much weaker than sampling conditions required by any known algorithm for producing a top...
Dominique Attali, André Lieutier