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» Reconstructing the pre-doubling genome
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CIE
2010
Springer
15 years 1 months ago
A Faster Algorithm for Finding Minimum Tucker Submatrices
A binary matrix has the Consecutive Ones Property (C1P) if its columns can be ordered in such a way that all 1s on each row are consecutive. Algorithmic issues of the C1P are centr...
Guillaume Blin, Romeo Rizzi, Stéphane Viale...
BIOINFORMATICS
2004
83views more  BIOINFORMATICS 2004»
14 years 9 months ago
Haplotypes histories as pathways of recombinations
Motivation: The diversity of a haplotype, represented as a string of polymorphic sites along a DNA sequence, increases exponentially with the number of sites if recombinations are...
Nadia El-Mabrouk, Damian Labuda
BMCBI
2007
148views more  BMCBI 2007»
14 years 10 months ago
Toward the automated generation of genome-scale metabolic networks in the SEED
Background: Current methods for the automated generation of genome-scale metabolic networks focus on genome annotation and preliminary biochemical reaction network assembly, but d...
Matthew DeJongh, Kevin Formsma, Paul Boillot, John...
BMCBI
2008
86views more  BMCBI 2008»
14 years 9 months ago
Is plant mitochondrial RNA editing a source of phylogenetic incongruence? An answer from in silico and in vivo data sets
Background: In plant mitochondria, the post-transcriptional RNA editing process converts C to U at a number of specific sites of the mRNA sequence and usually restores phylogeneti...
Ernesto Picardi, Carla Quagliariello
BMCBI
2006
87views more  BMCBI 2006»
14 years 9 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen