142 search results - page 22 / 29 » Reconstruction of Ancestral Genomic Sequences Using Likeliho... |
BIOINFORMATICS
2010
14 years 9 months ago
2010
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
121
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BMCBI
2011
14 years 4 months ago
2011
Background: High-throughput re-sequencing, new genotyping technologies and the availability of reference genomes allow the extensive characterization of Single Nucleotide Polymorp...
WABI
2007
Springer
15 years 3 months ago
2007
Springer
Although snake venom proteins have been proven instrumental in the design of blood clotting and cytostatic breast cancer drugs, the main method in use to sequence these unknown pr...
100
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NAR
2011
14 years 14 days ago
2011
The growing availability of complete genomic sequences from diverse species has brought about the need to scale up phylogenomic analyses, including the reconstruction of large col...
78
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BMCBI
2006
14 years 9 months ago
2006
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...