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BMCBI
2006
143views more  BMCBI 2006»
14 years 9 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
BMCBI
2011
14 years 1 months ago
Predicting mutually exclusive spliced exons based on exon length, splice site and reading frame conservation, and exon sequence
Background: Alternative splicing of pre-mature RNA is an important process eukaryotes utilize to increase their repertoire of different protein products. Several types of differen...
Holger Pillmann, Klas Hatje, Florian Odronitz, Bjo...
BMCBI
2007
135views more  BMCBI 2007»
14 years 9 months ago
Automatic extraction of reliable regions from multiple sequence alignments
Background: High quality multiple alignments are crucial in the transfer of annotation from one genome to another. Multiple alignment methods strive to achieve ever increasing lev...
Timo Lassmann, Erik L. L. Sonnhammer
NAR
2007
81views more  NAR 2007»
14 years 9 months ago
Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation
The Pseudogene.org database serves as a comprehensive repository for pseudogene sequence annotation. The definition of a pseudogene varies within the literature, resulting in sign...
John E. Karro, Yangpan Yan, Deyou Zheng, Zhaolei Z...
BMCBI
2010
185views more  BMCBI 2010»
14 years 9 months ago
ABCtoolbox: a versatile toolkit for approximate Bayesian computations
Background: The estimation of demographic parameters from genetic data often requires the computation of likelihoods. However, the likelihood function is computationally intractab...
Daniel Wegmann, Christoph Leuenberger, Samuel Neue...