Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
Background: Alternative splicing of pre-mature RNA is an important process eukaryotes utilize to increase their repertoire of different protein products. Several types of differen...
Background: High quality multiple alignments are crucial in the transfer of annotation from one genome to another. Multiple alignment methods strive to achieve ever increasing lev...
The Pseudogene.org database serves as a comprehensive repository for pseudogene sequence annotation. The definition of a pseudogene varies within the literature, resulting in sign...
John E. Karro, Yangpan Yan, Deyou Zheng, Zhaolei Z...
Background: The estimation of demographic parameters from genetic data often requires the computation of likelihoods. However, the likelihood function is computationally intractab...
Daniel Wegmann, Christoph Leuenberger, Samuel Neue...