Background: As one of the most widely used parsimony methods for ancestral reconstruction, the Fitch method minimizes the total number of hypothetical substitutions along all bran...
Jialiang Yang, Jun Li, Liuhuan Dong, Stefan Gr&uum...
We propose a dictionary model for haplotypes. According to the model, a haplotype is constructed by randomly concatenating haplotype segments from a given dictionary of segments. ...
There has been considerable recent interest in the use of haplotype structure to aid in the design and analysis of case-control association studies searching for genetic predictors...
Protein chimerism is a phenomenon involving the combination of multiple ancestral sequences into a single, multi-domain protein through evolution. We propose a novel method for de...
Background: We present here the PhIGs database, a phylogenomic resource for sequenced genomes. Although many methods exist for clustering gene families, very few attempt to create...