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» Reconstruction of Ancestral Genomic Sequences Using Likeliho...
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NAR
2000
120views more  NAR 2000»
14 years 9 months ago
WIT: integrated system for high-throughput genome sequence analysis and metabolic reconstruction
The WIT (What Is There) (http://wit.mcs.anl.gov/WIT2/ ) system has been designed to support comparative analysis of sequenced genomes and to generate metabolic reconstructions bas...
Ross A. Overbeek, Niels Larsen, Gordon D. Pusch, M...
ISMB
2000
14 years 11 months ago
UTR Reconstruction and Analysis Using Genomically Aligned EST Sequences
Zhengyan Kan, Warren Gish, Eric C. Rouchka, Jarret...
94
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WEA
2007
Springer
114views Algorithms» more  WEA 2007»
15 years 3 months ago
Improving Tree Search in Phylogenetic Reconstruction from Genome Rearrangement Data
Abstract. A major task in evolutionary biology is to determine the ancestral relationships among the known species, a process generally referred as phylogenetic reconstruction. In ...
Fei Ye, Yan Guo, Andrew Lawson, Jijun Tang
69
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BIOINFORMATICS
2004
83views more  BIOINFORMATICS 2004»
14 years 9 months ago
Haplotypes histories as pathways of recombinations
Motivation: The diversity of a haplotype, represented as a string of polymorphic sites along a DNA sequence, increases exponentially with the number of sites if recombinations are...
Nadia El-Mabrouk, Damian Labuda
WABI
2001
Springer
15 years 2 months ago
A Chemical-Distance-Based Test for Positive Darwinian Selection
There are very few instances in which positive Darwinian selection has been convincingly demonstrated at the molecular level. In this study, we present a novel test for detecting p...
Tal Pupko, Roded Sharan, Masami Hasegawa, Ron Sham...