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139
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BMCBI
2002
126views more  BMCBI 2002»
15 years 2 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy
140
Voted
EC
2000
187views ECommerce» more  EC 2000»
15 years 2 months ago
Comparison of Multiobjective Evolutionary Algorithms: Empirical Results
In this paper, we provide a systematic comparison of various evolutionary approaches to multiobjective optimization using six carefully chosen test functions. Each test function i...
Eckart Zitzler, Kalyanmoy Deb, Lothar Thiele
156
Voted
TJS
2002
160views more  TJS 2002»
15 years 2 months ago
Adaptive Optimizing Compilers for the 21st Century
Historically, compilers have operated by applying a fixed set of optimizations in a predetermined order. We call such an ordered list of optimizations a compilation sequence. This...
Keith D. Cooper, Devika Subramanian, Linda Torczon
167
Voted
SIAMCOMP
2010
174views more  SIAMCOMP 2010»
15 years 1 months ago
On the Complexity of Nash Equilibria and Other Fixed Points
We reexamine what it means to compute Nash equilibria and, more generally, what it means to compute a fixed point of a given Brouwer function, and we investigate the complexity o...
Kousha Etessami, Mihalis Yannakakis
173
Voted
BMCBI
2011
14 years 9 months ago
A lightweight, flow-based toolkit for parallel and distributed bioinformatics pipelines
Background: Bioinformatic analyses typically proceed as chains of data-processing tasks. A pipeline, or ‘workflow’, is a well-defined protocol, with a specific structure defin...
Marcin Cieslik, Cameron Mura