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BIOINFORMATICS
2004
119views more  BIOINFORMATICS 2004»
15 years 1 months ago
Analysis of variance components in gene expression data
Motivation: A microarray experiment is a multi-step process, and each step is a potential source of variation. There are two major sources of variation: biological variation and t...
James J. Chen, Robert R. Delongchamp, Chen-An Tsai...
BMCBI
2004
143views more  BMCBI 2004»
15 years 1 months ago
Comparing functional annotation analyses with Catmap
Background: Ranked gene lists from microarray experiments are usually analysed by assigning significance to predefined gene categories, e.g., based on functional annotations. Tool...
Thomas Breslin, Patrik Edén, Morten Krogh
BMCBI
2002
195views more  BMCBI 2002»
15 years 1 months ago
Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study
Background: A method to evaluate and analyze the massive data generated by series of microarray experiments is of utmost importance to reveal the hidden patterns of gene expressio...
Junbai Wang, Jan Delabie, Hans Christian Aasheim, ...
BMCBI
2010
117views more  BMCBI 2010»
15 years 1 months ago
Beyond rotamers: a generative, probabilistic model of side chains in proteins
Background: Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution stru...
Tim Harder, Wouter Boomsma, Martin Paluszewski, Je...
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BMCBI
2008
125views more  BMCBI 2008»
15 years 1 months ago
SNPLims: a data management system for genome wide association studies
Background: Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample. The ava...
Alessandro Orro, Guia Guffanti, Erika Salvi, Fabio...