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BMCBI
2008
220views more  BMCBI 2008»
14 years 10 months ago
Gene prediction in metagenomic fragments: A large scale machine learning approach
Background: Metagenomics is an approach to the characterization of microbial genomes via the direct isolation of genomic sequences from the environment without prior cultivation. ...
Katharina J. Hoff, Maike Tech, Thomas Lingner, Rol...
BMCBI
2008
122views more  BMCBI 2008»
14 years 10 months ago
Determining gene expression on a single pair of microarrays
Background: In microarray experiments the numbers of replicates are often limited due to factors such as cost, availability of sample or poor hybridization. There are currently fe...
Robert W. Reid, Anthony A. Fodor
DKE
2008
109views more  DKE 2008»
14 years 10 months ago
Deterministic algorithms for sampling count data
Processing and extracting meaningful knowledge from count data is an important problem in data mining. The volume of data is increasing dramatically as the data is generated by da...
Hüseyin Akcan, Alex Astashyn, Hervé Br...
BMCBI
2006
145views more  BMCBI 2006»
14 years 10 months ago
GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
Kazuharu Arakawa, Yohei Yamada, Kosaku Shinoda, Yo...
BMCBI
2006
202views more  BMCBI 2006»
14 years 10 months ago
Spectral embedding finds meaningful (relevant) structure in image and microarray data
Background: Accurate methods for extraction of meaningful patterns in high dimensional data have become increasingly important with the recent generation of data types containing ...
Brandon W. Higgs, Jennifer W. Weller, Jeffrey L. S...
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