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142
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ESANN
2004
15 years 4 months ago
Sparse LS-SVMs using additive regularization with a penalized validation criterion
This paper is based on a new way for determining the regularization trade-off in least squares support vector machines (LS-SVMs) via a mechanism of additive regularization which ha...
Kristiaan Pelckmans, Johan A. K. Suykens, Bart De ...
136
Voted
BMCBI
2010
154views more  BMCBI 2010»
15 years 3 months ago
Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data
Background: A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine which DNA-b...
Robert C. McLeay, Timothy L. Bailey
132
Voted
BMCBI
2010
137views more  BMCBI 2010»
15 years 3 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
121
Voted
BMCBI
2010
118views more  BMCBI 2010»
15 years 3 months ago
Artificial neural networks for the prediction of peptide drift time in ion mobility mass spectrometry
Background: There is an increasing usage of ion mobility-mass spectrometry (IMMS) in proteomics. IMMS combines the features of ion mobility spectrometry (IMS) and mass spectrometr...
Bing Wang, Steve Valentine, Manolo Plasencia, Srir...
145
Voted
ECRA
2007
141views more  ECRA 2007»
15 years 3 months ago
A growth theory perspective on B2C e-commerce growth in Europe: An exploratory study
Information and communication technologies (ICTs) continue to have a profound effect on the economies and societies where they are used. In this article, we propose three related...
Shuchun Ho, Robert J. Kauffman, Ting-Peng Liang