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BMCBI
2007
101views more  BMCBI 2007»
13 years 6 months ago
Robust detection and verification of linear relationships to generate metabolic networks using estimates of technical errors
Background: The size and magnitude of the metabolome, the ratio between individual metabolites and the response of metabolic networks is controlled by multiple cellular factors. A...
Frank Kose, Jan Budczies, Matthias Holschneider, O...
KDD
2004
ACM
139views Data Mining» more  KDD 2004»
14 years 6 months ago
Learning a complex metabolomic dataset using random forests and support vector machines
Metabolomics is the omics science of biochemistry. The associated data include the quantitative measurements of all small molecule metabolites in a biological sample. These datase...
Young Truong, Xiaodong Lin, Chris Beecher
BMCBI
2008
188views more  BMCBI 2008»
13 years 6 months ago
anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data
Background: Compared to other omics techniques, quantitative metabolomics is still at its infancy. Complex sample preparation and analytical procedures render exact quantification...
Nicola Zamboni, Anne Kümmel, Matthias Heinema...
RECOMB
2004
Springer
14 years 6 months ago
Modeling and Analysis of Heterogeneous Regulation in Biological Networks
Abstract. In this study we propose a novel model for the representation of biological networks and provide algorithms for learning model parameters from experimental data. Our appr...
Irit Gat-Viks, Amos Tanay, Ron Shamir
BMCBI
2006
143views more  BMCBI 2006»
13 years 6 months ago
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms
Background: Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information nee...
Rainer König, Gunnar Schramm, Marcus Oswald, ...