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» Regulation probability method for gene selection
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BMCBI
2008
163views more  BMCBI 2008»
14 years 9 months ago
Gene Ontology term overlap as a measure of gene functional similarity
Background: The availability of various high-throughput experimental and computational methods allows biologists to rapidly infer functional relationships between genes. It is oft...
Meeta Mistry, Paul Pavlidis
CIBCB
2005
IEEE
14 years 11 months ago
A Transcriptional Approach to Gene Clustering
— We present an integrative method for clustering coregulated genes and elucidating their underlying regulatory mechanisms. We use multi-state partition functions and thermodynam...
Ilias Tagkopoulos
BMCBI
2007
111views more  BMCBI 2007»
14 years 9 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda
BMCBI
2006
156views more  BMCBI 2006»
14 years 9 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
BMCBI
2010
125views more  BMCBI 2010»
14 years 4 months ago
ProbFAST: Probabilistic Functional Analysis System Tool
Background: The post-genomic era has brought new challenges regarding the understanding of the organization and function of the human genome. Many of these challenges are centered...
Israel T. da Silva, Ricardo Z. N. Vêncio, Th...