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BMCBI
2006
153views more  BMCBI 2006»
15 years 4 months ago
Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...
BMCBI
2006
102views more  BMCBI 2006»
15 years 4 months ago
Taking U out, with two nucleases?
Background: REX1 and REX2 are protein components of the RNA editing complex (the editosome) and function as exouridylylases. The exact roles of REX1 and REX2 in the editosome are ...
I. Saira Mian, Elizabeth A. Worthey, Reza Salavati
BMCBI
2006
130views more  BMCBI 2006»
15 years 4 months ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
BMCBI
2006
101views more  BMCBI 2006»
15 years 4 months ago
Hierarchical modularity of nested bow-ties in metabolic networks
Background: The exploration of the structural topology and the organizing principles of genomebased large-scale metabolic networks is essential for studying possible relations bet...
Jing Zhao, Hong Yu, Jianhua Luo, Zhi-Wei Cao, Yi-X...
CN
2006
70views more  CN 2006»
15 years 4 months ago
Small-world characteristics of Internet topologies and implications on multicast scaling
Recent work has shown that the physical connectivity of the Internet exhibits small-world behavior. Characterizing such behavior is important not only for generating realistic Int...
Shudong Jin, Azer Bestavros
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