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BMCBI
2004
158views more  BMCBI 2004»
15 years 3 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...
BMCBI
2004
140views more  BMCBI 2004»
15 years 3 months ago
What can we learn from noncoding regions of similarity between genomes?
Background: In addition to known protein-coding genes, large amounts of apparently non-coding sequence are conserved between the human and mouse genomes. It seems reasonable to as...
Thomas A. Down, Tim J. P. Hubbard
BMCBI
2004
124views more  BMCBI 2004»
15 years 3 months ago
The Molecular Pages of the mesotelencephalic dopamine consortium (DopaNet)
Background: DopaNet http://www.dopanet.org is a Systems Biology initiative that aims to investigate precisely and quantitatively all the aspects of neurotransmission in a specific...
Nicolas Le Novère, Marco Donizelli
BMCBI
2004
153views more  BMCBI 2004»
15 years 3 months ago
Computational protein biomarker prediction: a case study for prostate cancer
Background: Recent technological advances in mass spectrometry pose challenges in computational mathematics and statistics to process the mass spectral data into predictive models...
Michael Wagner, Dayanand N. Naik, Alex Pothen, Sri...
BMCBI
2004
114views more  BMCBI 2004»
15 years 3 months ago
Extending the mutual information measure to rank inferred literature relationships
Background: Within the peer-reviewed literature, associations between two things are not always recognized until commonalities between them become apparent. These commonalities ca...
Jonathan D. Wren
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