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BMCBI
2007
14 years 10 months ago
2007
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
BMCBI
2008
14 years 10 months ago
2008
Background: While the C. elegans genome is extensively annotated, relatively little information is available for other Caenorhabditis species. The nematode genome annotation asses...
BMCBI
2008
14 years 10 months ago
2008
Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...
BMCBI
2007
2007
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
14 years 10 months ago
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
BMCBI
2008
14 years 10 months ago
2008
Background: The amount of information stemming from proteomics experiments involving (multi dimensional) separation techniques, mass spectrometric analysis, and computational anal...