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BMCBI
2008
138views more  BMCBI 2008»
14 years 10 months ago
M-BISON: Microarray-based integration of data sources using networks
Background: The accurate detection of differentially expressed (DE) genes has become a central task in microarray analysis. Unfortunately, the noise level and experimental variabi...
Bernie J. Daigle Jr., Russ B. Altman
BMCBI
2008
130views more  BMCBI 2008»
14 years 10 months ago
Structural descriptor database: a new tool for sequence-based functional site prediction
Background: The Structural Descriptor Database (SDDB) is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties o...
Juliana S. Bernardes, Jorge H. Fernandez, Ana Tere...
BMCBI
2008
138views more  BMCBI 2008»
14 years 10 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
BMCBI
2008
116views more  BMCBI 2008»
14 years 10 months ago
Gene Ontology annotations: what they mean and where they come from
To address the challenges of information integration and retrieval, the computational genomics community increasingly has come to rely on the methodology of creating annotations o...
David P. Hill, Barry Smith, Monica S. McAndrews-Hi...
BMCBI
2008
116views more  BMCBI 2008»
14 years 10 months ago
Structuring an event ontology for disease outbreak detection
Background: This paper describes the design of an event ontology being developed for application in the machine understanding of infectious disease-related events reported in natu...
Ai Kawazoe, Hutchatai Chanlekha, Mika Shigematsu, ...
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