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BMCBI
2006
94views more  BMCBI 2006»
14 years 9 months ago
Noise-injected neural networks show promise for use on small-sample expression data
Background: Overfitting the data is a salient issue for classifier design in small-sample settings. This is why selecting a classifier from a constrained family of classifiers, on...
Jianping Hua, James Lowey, Zixiang Xiong, Edward R...
BMCBI
2006
125views more  BMCBI 2006»
14 years 9 months ago
Development of an open source laboratory information management system for 2-D gel electrophoresis-based proteomics workflow
Background: In the post-genome era, most research scientists working in the field of proteomics are confronted with difficulties in management of large volumes of data, which they...
Hiraku Morisawa, Mikako Hirota, Tosifusa Toda
BMCBI
2006
118views more  BMCBI 2006»
14 years 9 months ago
Statistical analysis of an RNA titration series evaluates microarray precision and sensitivity on a whole-array basis
Background: Concerns are often raised about the accuracy of microarray technologies and the degree of cross-platform agreement, but there are yet no methods which can unambiguousl...
Andrew J. Holloway, Alicia Oshlack, Dileepa S. Diy...
BMCBI
2006
156views more  BMCBI 2006»
14 years 9 months ago
Detecting the limits of regulatory element conservation and divergence estimation using pairwise and multiple alignments
Background: Molecular evolutionary studies of noncoding sequences rely on multiple alignments. Yet how multiple alignment accuracy varies across sequence types, tree topologies, d...
Daniel A. Pollard, Alan M. Moses, Venky N. Iyer, M...
CN
2006
163views more  CN 2006»
14 years 9 months ago
A framework for mining evolving trends in Web data streams using dynamic learning and retrospective validation
The expanding and dynamic nature of the Web poses enormous challenges to most data mining techniques that try to extract patterns from Web data, such as Web usage and Web content....
Olfa Nasraoui, Carlos Rojas, Cesar Cardona
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