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BMCBI
2006
172views more  BMCBI 2006»
14 years 11 months ago
A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
Background: Tandem mass spectrometry (MS/MS) is a powerful tool for protein identification. Although great efforts have been made in scoring the correlation between tandem mass sp...
Zhuo Zhang, Shiwei Sun, Xiaopeng Zhu, Suhua Chang,...
101
Voted
JACM
2006
93views more  JACM 2006»
14 years 11 months ago
Combining expert advice in reactive environments
"Experts algorithms" constitute a methodology for choosing actions repeatedly, when the rewards depend both on the choice of action and on the unknown current state of t...
Daniela Pucci de Farias, Nimrod Megiddo
SIGMOD
2007
ACM
125views Database» more  SIGMOD 2007»
15 years 11 months ago
Optimizing mpf queries: decision support and probabilistic inference
Managing uncertain data using probabilistic frameworks has attracted much interest lately in the database literature, and a central computational challenge is probabilistic infere...
Héctor Corrada Bravo, Raghu Ramakrishnan
90
Voted
CMSB
2007
Springer
15 years 5 months ago
Expressive Models for Synaptic Plasticity
We explore some presynaptic mechanisms of the calyx of Held synapse through a stochastic model. The model, drawn from a kinetic approach developed in literature, exploits process c...
Andrea Bracciali, Marcello Brunelli, Enrico Catald...
BMCBI
2006
119views more  BMCBI 2006»
14 years 11 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs