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BMCBI
2010
2010
Towards the systematic discovery of signal transduction networks using phosphorylation dynamics data
14 years 10 months ago
Background: Phosphorylation is a ubiquitous and fundamental regulatory mechanism that controls signal transduction in living cells. The number of identified phosphoproteins and th...
BMCBI
2008
14 years 10 months ago
2008
Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
BMCBI
2008
14 years 10 months ago
2008
Background: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increas...
BMCBI
2010
14 years 10 months ago
2010
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
BMCBI
2010
2010
An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs
14 years 10 months ago
Background: Transcription factors (TFs) control transcription by binding to specific regions of DNA called transcription factor binding sites (TFBSs). The identification of TFBSs ...