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» Relational Parametricity and Control
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BMCBI
2010
132views more  BMCBI 2010»
14 years 9 months ago
Next generation tools for genomic data generation, distribution, and visualization
Background: With the rapidly falling cost and availability of high throughput sequencing and microarray technologies, the bottleneck for effectively using genomic analysis in the ...
David A. Nix, Tonya L. Di Sera, Brian K. Dalley, B...
BMCBI
2010
98views more  BMCBI 2010»
14 years 9 months ago
A semi-nonparametric mixture model for selecting functionally consistent proteins
Background: High-throughput technologies have led to a new era of proteomics. Although protein microarray experiments are becoming more common place there are a variety of experim...
Lianbo Yu, R. W. Doerge
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BMCBI
2008
114views more  BMCBI 2008»
14 years 9 months ago
Visualizing and clustering high throughput sub-cellular localization imaging
Background: The expansion of automatic imaging technologies has created a need to be able to efficiently compare and review large sets of image data. To enable comparisons of imag...
Nicholas A. Hamilton, Rohan D. Teasdale
BMCBI
2007
123views more  BMCBI 2007»
14 years 9 months ago
PedGenie: meta genetic association testing in mixed family and case-control designs
Background-: PedGenie software, introduced in 2006, includes genetic association testing of cases and controls that may be independent or related (nuclear families or extended ped...
Karen Curtin, Jathine Wong, Kristina Allen-Brady, ...
BMCBI
2007
86views more  BMCBI 2007»
14 years 9 months ago
Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
William O. Ward, Carol D. Swartz, Steffen Porwolli...