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BMCBI
2006
114views more  BMCBI 2006»
14 years 10 months ago
Mining frequent patterns for AMP-activated protein kinase regulation on skeletal muscle
Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
Qingfeng Chen, Yi-Ping Phoebe Chen
BMCBI
2006
159views more  BMCBI 2006»
14 years 10 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
IPM
2007
137views more  IPM 2007»
14 years 9 months ago
Analyzing imbalance among homogeneous index servers in a web search system
The performance of parallel query processing in a cluster of index servers is crucial for modern web search systems. In such a scenario, the response time basically depends on the...
Claudine Santos Badue, Ricardo A. Baeza-Yates, Ber...
JBI
2007
120views Bioinformatics» more  JBI 2007»
14 years 9 months ago
Measures of semantic similarity and relatedness in the biomedical domain
Measures of semantic similarity between concepts are widely used in Natural Language Processing. In this article, we show how six existing domain-independent measures can be adapt...
Ted Pedersen, Serguei V. S. Pakhomov, Siddharth Pa...
BMCBI
2004
114views more  BMCBI 2004»
14 years 9 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....