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    BMCBI
    2007
    103views more  BMCBI 2007»
    eQTL Viewer: visualizing how sequence variation affects genome-wide transcription
    14 years 9 months ago
    eQTL Viewer: visualizing how sequence variation affects genome-wide transcription
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    Background: Expression Quantitative Trait Locus (eQTL) mapping methods have been used to identify the genetic basis of gene expression variations. To map eQTL, thousands of expres...
    Wei Zou, David L. Aylor, Zhao-Bang Zeng
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    BMCBI
    2008
    127views more  BMCBI 2008»
    MetaMine - A tool to detect and analyse gene patterns in their environmental context
    14 years 9 months ago
    MetaMine - A tool to detect and analyse gene patterns in their environmental context
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    Background: Modern sequencing technologies allow rapid sequencing and bioinformatic analysis of genomes and metagenomes. With every new sequencing project a vast number of new pro...
    Uta Bohnebeck, Thierry Lombardot, Renzo Kottmann, ...
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    BMCBI
    2008
    129views more  BMCBI 2008»
    Prediction of the outcome of preoperative chemotherapy in breast cancer using DNA probes that provide information on both comple
    14 years 9 months ago
    Prediction of the outcome of preoperative chemotherapy in breast cancer using DNA probes that provide information on both comple
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    Background: DNA microarray technology has emerged as a major tool for exploring cancer biology and solving clinical issues. Predicting a patient's response to chemotherapy is...
    René Natowicz, Roberto Incitti, Euler Guima...
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    BMCBI
    2008
    114views more  BMCBI 2008»
    Partial mixture model for tight clustering of gene expression time-course
    14 years 9 months ago
    Partial mixture model for tight clustering of gene expression time-course
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    Background: Tight clustering arose recently from a desire to obtain tighter and potentially more informative clusters in gene expression studies. Scattered genes with relatively l...
    Yinyin Yuan, Chang-Tsun Li, Roland Wilson
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    BMCBI
    2008
    87views more  BMCBI 2008»
    Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfa
    14 years 9 months ago
    Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfa
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    Background: Empirical binding models have previously been investigated for the energetics of protein complexation (G models) and for the influence of mutations on complexation (i....
    Salim Bougouffa, Jim Warwicker
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