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BMCBI
2004
114views more  BMCBI 2004»
14 years 9 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
BMCBI
2004
122views more  BMCBI 2004»
14 years 9 months ago
A comprehensive comparison of comparative RNA structure prediction approaches
Background: An increasing number of researchers have released novel RNA structure analysis and prediction algorithms for comparative approaches to structure prediction. Yet, indep...
Paul P. Gardner, Robert Giegerich
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BMCBI
2004
141views more  BMCBI 2004»
14 years 9 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
BMCBI
2004
144views more  BMCBI 2004»
14 years 9 months ago
PASBio: predicate-argument structures for event extraction in molecular biology
Background: The exploitation of information extraction (IE), a technology aiming to provide instances of structured representations from free-form text, has been rapidly growing w...
Tuangthong Wattarujeekrit, Parantu K. Shah, Nigel ...
BMCBI
2004
142views more  BMCBI 2004»
14 years 9 months ago
GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies
Background: Microarray and other high-throughput technologies are producing large sets of interesting genes that are difficult to analyze directly. Bioinformatics tools are needed...
Bing Zhang, Denise Schmoyer, Stefan Kirov, Jay Sno...
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