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» Relative Entropy and Statistics
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96
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BMCBI
2007
125views more  BMCBI 2007»
15 years 24 days ago
Statistical tests to compare motif count exceptionalities
Background: Finding over- or under-represented motifs in biological sequences is now a common task in genomics. Thanks to p-value calculation for motif counts, exceptional motifs ...
Stéphane Robin, Sophie Schbath, Vincent Van...
117
Voted
BMCBI
2004
150views more  BMCBI 2004»
15 years 16 days ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...
115
Voted
WEBI
2005
Springer
15 years 6 months ago
HITS is Principal Components Analysis
In this work, we show that Kleinberg’s hubs and authorities model (HITS) is simply Principal Components Analysis (PCA; maybe the most widely used multivariate statistical analys...
Marco Saerens, François Fouss
EOR
2006
113views more  EOR 2006»
15 years 21 days ago
Validation of regression metamodels in simulation: Bootstrap approach
Simulation experiments are often analyzed through a linear regression model of their input/output data. Such an analysis yields a metamodel or response surface for the underlying ...
Jack P. C. Kleijnen, David Deflandre
121
Voted
BMCBI
2007
147views more  BMCBI 2007»
15 years 24 days ago
Statistical significance of quantitative PCR
Background: PCR has the potential to detect and precisely quantify specific DNA sequences, but it is not yet often used as a fully quantitative method. A number of data collection...
Yann Karlen, Alan McNair, Sébastien Persegu...