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BMCBI
2010
133views more  BMCBI 2010»
15 years 4 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
BMCBI
2008
170views more  BMCBI 2008»
15 years 4 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou
BMCBI
2006
121views more  BMCBI 2006»
15 years 4 months ago
Robust computational reconstitution - a new method for the comparative analysis of gene expression in tissues and isolated cell
Background: Biological tissues consist of various cell types that differentially contribute to physiological and pathophysiological processes. Determining and analyzing cell type-...
Martin Hoffmann, Dirk Pohlers, Dirk Koczan, Hans-J...
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CSDA
2006
191views more  CSDA 2006»
15 years 4 months ago
Forecasting daily time series using periodic unobserved components time series models
We explore a periodic analysis in the context of unobserved components time series models that decompose time series into components of interest such as trend, seasonal and irregu...
Siem Jan Koopman, Marius Ooms
SIGIR
2008
ACM
15 years 3 months ago
Enhancing text clustering by leveraging Wikipedia semantics
Most traditional text clustering methods are based on "bag of words" (BOW) representation based on frequency statistics in a set of documents. BOW, however, ignores the ...
Jian Hu, Lujun Fang, Yang Cao, Hua-Jun Zeng, Hua L...