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BMCBI
2007
91views more  BMCBI 2007»
15 years 4 months ago
A mass accuracy sensitive probability based scoring algorithm for database searching of tandem mass spectrometry data
Background: Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) has become one of the most used tools in mass spectrometry based proteomics. Various algorithms ...
Hua Xu, Michael A. Freitas
BMCBI
2010
132views more  BMCBI 2010»
15 years 4 months ago
Consistency, comprehensiveness, and compatibility of pathway databases
Background: It is necessary to analyze microarray experiments together with biological information to make better biological inferences. We investigate the adequacy of current bio...
Donny Soh, Difeng Dong, Yike Guo, Limsoon Wong
BMCBI
2010
98views more  BMCBI 2010»
15 years 4 months ago
A semi-nonparametric mixture model for selecting functionally consistent proteins
Background: High-throughput technologies have led to a new era of proteomics. Although protein microarray experiments are becoming more common place there are a variety of experim...
Lianbo Yu, R. W. Doerge
BMCBI
2007
185views more  BMCBI 2007»
15 years 4 months ago
GEDI: a user-friendly toolbox for analysis of large-scale gene expression data
Background: Several mathematical and statistical methods have been proposed in the last few years to analyze microarray data. Most of those methods involve complicated formulas, a...
André Fujita, João Ricardo Sato, Car...
BMCBI
2008
128views more  BMCBI 2008»
15 years 4 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson