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BMCBI
2006
183views more  BMCBI 2006»
15 years 17 days ago
Mining gene expression data by interpreting principal components
Background: There are many methods for analyzing microarray data that group together genes having similar patterns of expression over all conditions tested. However, in many insta...
Joseph C. Roden, Brandon W. King, Diane Trout, Ali...
120
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BMCBI
2006
143views more  BMCBI 2006»
15 years 17 days ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
95
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BMCBI
2007
103views more  BMCBI 2007»
15 years 16 days ago
Systems biology approach for mapping the response of human urothelial cells to infection by Enterococcus faecalis
Background: To better understand the response of urinary epithelial (urothelial) cells to Enterococcus faecalis, a uropathogen that exhibits resistance to multiple antibiotics, a ...
Mikhail G. Dozmorov, Kimberly D. Kyker, Ricardo Sa...
JCB
2006
185views more  JCB 2006»
15 years 14 days ago
A Probabilistic Methodology for Integrating Knowledge and Experiments on Biological Networks
Biological systems are traditionally studied by focusing on a specific subsystem, building an intuitive model for it, and refining the model using results from carefully designed ...
Irit Gat-Viks, Amos Tanay, Daniela Raijman, Ron Sh...
BMCBI
2005
82views more  BMCBI 2005»
15 years 12 days ago
Quality assessment of microarrays: Visualization of spatial artifacts and quantitation of regional biases
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...
Mark Reimers, John N. Weinstein