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BMCBI
2010
139views more  BMCBI 2010»
15 years 1 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2008
152views more  BMCBI 2008»
15 years 1 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
BMCBI
2008
136views more  BMCBI 2008»
15 years 1 months ago
GPAT: Retrieval of genomic annotation from large genomic position datasets
Background: Recent genome wide transcription factor binding site or chromatin modification mapping analysis techniques, such as chromatin immunoprecipitation (ChIP) linked to DNA ...
Arnaud Krebs, Mattia Frontini, Làszlò...
DSS
2007
113views more  DSS 2007»
15 years 1 months ago
An associate constraint network approach to extract multi-lingual information for crime analysis
International crime and terrorism have drawn increasing attention in recent years. Retrieving relevant information from criminal records and suspect communications is important in...
Christopher C. Yang, Kar Wing Li
TCBB
2010
136views more  TCBB 2010»
14 years 12 months ago
Efficient Extraction of Protein-Protein Interactions from Full-Text Articles
—Proteins and their interactions govern virtually all cellular processes, such as regulation, signaling, metabolism, and structure. Most experimental findings pertaining to such ...
Jörg Hakenberg, Robert Leaman, Nguyen Ha Vo, ...