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» Removing the Genetics from the Standard Genetic Algorithm
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KDD
2008
ACM
181views Data Mining» more  KDD 2008»
15 years 10 months ago
Fastanova: an efficient algorithm for genome-wide association study
Studying the association between quantitative phenotype (such as height or weight) and single nucleotide polymorphisms (SNPs) is an important problem in biology. To understand und...
Xiang Zhang, Fei Zou, Wei Wang 0010
BMCBI
2010
161views more  BMCBI 2010»
14 years 7 months ago
LTC: a novel algorithm to improve the efficiency of contig assembly for physical mapping in complex genomes
Background: Physical maps are the substrate of genome sequencing and map-based cloning and their construction relies on the accurate assembly of BAC clones into large contigs that...
Zeev Frenkel, Etienne Paux, David I. Mester, Cathe...
LION
2009
Springer
160views Optimization» more  LION 2009»
15 years 4 months ago
Corridor Selection and Fine Tuning for the Corridor Method
In this paper we present a novel hybrid algorithm, in which ideas from the genetic algorithm and the GRASP metaheuristic are cooperatively used and intertwined to dynamically adjus...
Marco Caserta, Stefan Voß
GECCO
2008
Springer
158views Optimization» more  GECCO 2008»
14 years 11 months ago
Structure and parameter estimation for cell systems biology models
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...
Francisco José Romero-Campero, Hongqing Cao...
RECOMB
2008
Springer
15 years 10 months ago
Accounting for Non-genetic Factors Improves the Power of eQTL Studies
Abstract. The recent availability of large scale data sets profiling single nucleotide polymorphisms (SNPs) and gene expression across different human populations, has directed muc...
Oliver Stegle, Anitha Kannan, Richard Durbin, John...