52 search results - page 8 / 11 » Repeat-aware Comparative Genome Assembly |
BMCBI
2005
14 years 9 months ago
2005
Background: Accurate and automatic gene finding and structural prediction is a common problem in bioinformatics, and applications need to be capable of handling non-canonical spli...
103
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BMCBI
2007
14 years 9 months ago
2007
Background: Current methods for the automated generation of genome-scale metabolic networks focus on genome annotation and preliminary biochemical reaction network assembly, but d...
115
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BMCBI
2011
14 years 4 months ago
2011
Background: Computational analysis of metagenomes requires the taxonomical assignment of the genome contigs assembled from DNA reads of environmental samples. Because of the diver...
BMCBI
2007
14 years 9 months ago
2007
Background: Sequence comparison faces new challenges today, with many complete genomes and large libraries of transcripts known. Gene annotation pipelines match these sequences in...
BMCBI
2008
14 years 9 months ago
2008
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome [1] would not have been p...