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BMCBI
2010
136views more  BMCBI 2010»
14 years 11 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2007
117views more  BMCBI 2007»
14 years 11 months ago
Application of a correlation correction factor in a microarray cross-platform reproducibility study
Background: Recent research examining cross-platform correlation of gene expression intensities has yielded mixed results. In this study, we demonstrate use of a correction factor...
Kellie J. Archer, Catherine I. Dumur, G. Scott Tay...
BMCBI
2008
185views more  BMCBI 2008»
14 years 11 months ago
Mining clinical relationships from patient narratives
Background: The Clinical E-Science Framework (CLEF) project has built a system to extract clinically significant information from the textual component of medical records in order...
Angus Roberts, Robert J. Gaizauskas, Mark Hepple, ...
BMCBI
2006
102views more  BMCBI 2006»
14 years 11 months ago
MycoperonDB: a database of computationally identified operons and transcriptional units in Mycobacteria
Background: A key post genomics challenge is to identify how genes in an organism come together and perform physiological functions. An important first step in this direction is t...
Sarita Ranjan, Ranjit Kumar Gundu, Akash Ranjan
CPHYSICS
2007
106views more  CPHYSICS 2007»
14 years 11 months ago
The way towards thermonuclear fusion simulators
In parallel to the ITER project itself, many initiatives address complementary technological issues relevant to a fusion reactor, as well as many remaining scientific issues. One...
A. Bécoulet, Per Strand, H. Wilson, M. Roma...