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BMCBI
2008
129views more  BMCBI 2008»
14 years 9 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
BMCBI
2006
144views more  BMCBI 2006»
14 years 9 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...
RECOMB
2004
Springer
15 years 10 months ago
A class of edit kernels for SVMs to predict translation initiation sites in eukaryotic mRNAs
The prediction of translation initiation sites (TISs) in eukaryotic mRNAs has been a challenging problem in computational molecular biology. In this paper, we present a new algori...
Haifeng Li, Tao Jiang
BMCBI
2010
129views more  BMCBI 2010»
14 years 9 months ago
A temporal precedence based clustering method for gene expression microarray data
Background: Time-course microarray experiments can produce useful data which can help in understanding the underlying dynamics of the system. Clustering is an important stage in m...
Ritesh Krishna, Chang-Tsun Li, Vicky Buchanan-Woll...
BMCBI
2007
102views more  BMCBI 2007»
14 years 9 months ago
qPIPSA: Relating enzymatic kinetic parameters and interaction fields
Background: The simulation of metabolic networks in quantitative systems biology requires the assignment of enzymatic kinetic parameters. Experimentally determined values are ofte...
Razif R. Gabdoulline, Matthias Stein, Rebecca C. W...