Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey
Background: Availability of information about transcription factors (TFs) is crucial for genome biology, as TFs play a central role in the regulation of gene expression. While man...
Background: An important class of interaction switches for biological circuits and disease pathways are short binding motifs. However, the biological experiments to find these bin...
Soon-Heng Tan, Hugo Willy, Wing-Kin Sung, See-Kion...
Uncertainty in categorical data is commonplace in many applications, including data cleaning, database integration, and biological annotation. In such domains, the correct value o...
Sarvjeet Singh, Chris Mayfield, Sunil Prabhakar, R...
Background: Elucidating the dynamic behaviour of genetic regulatory networks is one of the most significant challenges in systems biology. However, conventional quantitative predi...