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BMCBI
2010
97views more  BMCBI 2010»
14 years 9 months ago
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey
BMCBI
2008
134views more  BMCBI 2008»
14 years 9 months ago
Identification of transcription factor contexts in literature using machine learning approaches
Background: Availability of information about transcription factors (TFs) is crucial for genome biology, as TFs play a central role in the regulation of gene expression. While man...
Hui Yang, Goran Nenadic, John A. Keane
BMCBI
2006
112views more  BMCBI 2006»
14 years 9 months ago
A correlated motif approach for finding short linear motifs from protein interaction networks
Background: An important class of interaction switches for biological circuits and disease pathways are short binding motifs. However, the biological experiments to find these bin...
Soon-Heng Tan, Hugo Willy, Wing-Kin Sung, See-Kion...
ICDE
2007
IEEE
104views Database» more  ICDE 2007»
15 years 11 months ago
Indexing Uncertain Categorical Data
Uncertainty in categorical data is commonplace in many applications, including data cleaning, database integration, and biological annotation. In such domains, the correct value o...
Sarvjeet Singh, Chris Mayfield, Sunil Prabhakar, R...
BMCBI
2005
122views more  BMCBI 2005»
14 years 9 months ago
A microarray data-based semi-kinetic method for predicting quantitative dynamics of genetic networks
Background: Elucidating the dynamic behaviour of genetic regulatory networks is one of the most significant challenges in systems biology. However, conventional quantitative predi...
Katsuyuki Yugi, Yoichi Nakayama, Shigen Kojima, To...