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» Representing Process Variation with a Process Family
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BMCBI
2007
130views more  BMCBI 2007»
14 years 9 months ago
Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base
Background: G Protein-Coupled Receptors (GPCRs) are a large and diverse family of membrane proteins whose members participate in the regulation of most cellular and physiological ...
Lucy Skrabanek, Marta Murcia, Michel Bouvier, Laks...
BMCBI
2008
103views more  BMCBI 2008»
14 years 9 months ago
Detection of protein catalytic residues at high precision using local network properties
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...
Patrick Slama, Ioannis Filippis, Michael Lappe
BMCBI
2008
118views more  BMCBI 2008»
14 years 9 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
BMCBI
2007
110views more  BMCBI 2007»
14 years 9 months ago
Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy
Background: The design of long oligonucleotides for spotted DNA microarrays requires detailed attention to ensure their optimal performance in the hybridization process. The main ...
Guangan Hu, Manuel Llinás, Jingguang Li, Pe...
CVPR
2010
IEEE
15 years 5 months ago
Curious Snakes: a minimum-latency solution to the cluttered background problem in active contours
We present a region-based active contour detection algorithm for objects that exhibit relatively homogeneous photometric characteristics (e.g. smooth color or gray levels), embe...
Ganesh Sundaramoorthi, Stefano Soatto, Anthony Yez...