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143
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BIOINFORMATICS
2008
15 years 1 months ago
2008
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
153
Voted
BIOINFORMATICS
2008
15 years 1 months ago
2008
Motivation: Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between...
144
Voted
BMCBI
2010
15 years 1 months ago
2010
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
152
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BMCBI
2010
15 years 1 months ago
2010
Background: Analysis of data from high-throughput experiments depends on the availability of well-structured data that describe the assayed biomolecules. Procedures for obtaining ...
135
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BMCBI
2010
15 years 1 months ago
2010
Background: Identifying candidate genes in genetic networks is important for understanding regulation and biological function. Large gene expression datasets contain relevant info...