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BMCBI
2010
116views more  BMCBI 2010»
14 years 9 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
BMCBI
2007
135views more  BMCBI 2007»
14 years 9 months ago
DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput
Background: Due to the complex and distributed nature of biological research, our current biological knowledge is spread over many redundant annotation databases maintained by man...
Brad T. Sherman, Da Wei Huang, Qina Tan, Yongjian ...
69
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BMCBI
2008
77views more  BMCBI 2008»
14 years 9 months ago
Stochastic models for the in silico simulation of synaptic processes
Background: Research in life sciences is benefiting from a large availability of formal description techniques and analysis methodologies. These allow both the phenomena investiga...
Andrea Bracciali, Marcello Brunelli, Enrico Catald...
87
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GPEM
2007
119views more  GPEM 2007»
14 years 9 months ago
Genomic mining for complex disease traits with "random chemistry"
Our rapidly growing knowledge regarding genetic variation in the human genome offers great potential for understanding the genetic etiology of disease. This, in turn, could revolut...
Margaret J. Eppstein, Joshua L. Payne, Bill C. Whi...
PR
2006
164views more  PR 2006»
14 years 9 months ago
Locally linear metric adaptation with application to semi-supervised clustering and image retrieval
Many computer vision and pattern recognition algorithms are very sensitive to the choice of an appropriate distance metric. Some recent research sought to address a variant of the...
Hong Chang, Dit-Yan Yeung