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BMCBI
2010
138views more  BMCBI 2010»
14 years 10 months ago
A database and API for variation, dense genotyping and resequencing data
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
Daniel Rios, William M. McLaren, Yuan Chen, Ewan B...
BMCBI
2010
96views more  BMCBI 2010»
14 years 10 months ago
Incorporating gene co-expression network in identification of cancer prognosis markers
Background: Extensive biomedical studies have shown that clinical and environmental risk factors may not have sufficient predictive power for cancer prognosis. The development of ...
Shuangge Ma, Mingyu Shi, Yang Li, Danhui Yi, Ben-C...
BMCBI
2010
183views more  BMCBI 2010»
14 years 10 months ago
SING: Subgraph search In Non-homogeneous Graphs
Background: Finding the subgraphs of a graph database that are isomorphic to a given query graph has practical applications in several fields, from cheminformatics to image unders...
Raffaele Di Natale, Alfredo Ferro, Rosalba Giugno,...
BMCBI
2010
130views more  BMCBI 2010»
14 years 10 months ago
Amino acid "little Big Bang": Representing amino acid substitution matrices as dot products of Euclidian vectors
Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
Karel Zimmermann, Jean-François Gibrat
BMCBI
2010
103views more  BMCBI 2010»
14 years 10 months ago
Detecting internally symmetric protein structures
Background: Many functional proteins have a symmetric structure. Most of these are multimeric complexes, which are made of non-symmetric monomers arranged in a symmetric manner. H...
Changhoon Kim, Jodi Basner, Byungkook Lee
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