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109
Voted
BMCBI
2005
15 years 18 days ago
2005
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
109
Voted
BMCBI
2005
15 years 18 days ago
2005
Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...
124
Voted
BMCBI
2005
15 years 18 days ago
2005
Background: With microarray technology the expression of thousands of genes can be measured simultaneously. It is well known that the expression levels of genes of interacting pro...
122
Voted
BMCBI
2005
15 years 18 days ago
2005
Background: Normal mode analysis (NMA) has become the method of choice to investigate the slowest motions in macromolecular systems. NMA is especially useful for large biomolecula...
104
Voted
BMCBI
2005
15 years 18 days ago
2005
Background: With the explosion of microarray studies, an enormous amount of data is being produced. Systematic integration of gene expression data from different sources increases...