Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
Background: Protein sequence motifs are by definition short fragments of conserved amino acids, often associated with a specific function. Accordingly protein sequence profiles de...
Jan Hummel, Nima Keshvari, Wolfram Weckwerth, Joac...
Background: Translational research requires taking basic science observations and developing them into clinically useful tests and therapeutics. We have developed a process to dev...
Robert Kim, Francesca Demichelis, Jeffery Tang, Al...
Background: Interpreting the results of high-throughput experiments, such as those obtained from DNA-microarrays, is an often time-consuming task due to the high number of data-po...
Felix Kokocinski, Nicolas Delhomme, Gunnar Wrobel,...
Background: The PD-(D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is o...