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BMCBI
2007
107views more  BMCBI 2007»
13 years 6 months ago
Reuse of structural domain-domain interactions in protein networks
Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...
Benjamin Schuster-Böckler, Alex Bateman
ECCB
2008
IEEE
14 years 23 days ago
Functional coherence in domain interaction networks
Motivation: Extracting functional information from protein–protein interactions (PPI) poses significant challenges arising from the noisy, incomplete, generic and static nature...
Jayesh Pandey, Mehmet Koyutürk, Shankar Subra...
BMCBI
2006
133views more  BMCBI 2006»
13 years 6 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
AINA
2009
IEEE
14 years 1 months ago
The Small-World Model for Amino Acid Interaction Networks
—In this paper we introduce the notion of protein interaction network. This is a graph whose vertices are the protein’s amino acids and whose edges are the interactions between...
Omar Gaci, Stefan Balev
BMCBI
2004
174views more  BMCBI 2004»
13 years 6 months ago
Implications for domain fusion protein-protein interactions based on structural information
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Jer-Ming Chia, Prasanna R. Kolatkar