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104
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CAINE
2007
15 years 5 months ago
Systems Modeling of Alveolar Morphogenesis In Vitro
We present a pulmonary alveolar epithelial cell model and its simulation results aimed to provide mechanistic insight into biological principles that underlie alveolar morphogenes...
Sean H. J. Kim, Sunwoo Park, Wei Yu, Keith E. Most...
187
Voted
APVIS
2009
15 years 4 months ago
Visualization of signal transduction processes in the crowded environment of the cell
In this paper, we propose a stochastic simulation to model and analyze cellular signal transduction. The high number of objects in a simulation requires advanced visualization tec...
Martin Falk, Michael Klann, Matthias Reuss, Thomas...
133
Voted
BMCBI
2010
185views more  BMCBI 2010»
15 years 3 months ago
ABCtoolbox: a versatile toolkit for approximate Bayesian computations
Background: The estimation of demographic parameters from genetic data often requires the computation of likelihoods. However, the likelihood function is computationally intractab...
Daniel Wegmann, Christoph Leuenberger, Samuel Neue...
153
Voted
BMCBI
2007
114views more  BMCBI 2007»
15 years 3 months ago
Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
Xiaohua Hu, Fang-Xiang Wu
FGCS
2006
74views more  FGCS 2006»
15 years 3 months ago
A performance model of non-deterministic particle transport on large-scale systems
In this work we present a predictive analytical model that encompasses the performance and scaling characteristics of a nondeterministic particle transport application, MCNP (Mont...
Mark M. Mathis, Darren J. Kerbyson, Adolfy Hoisie