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BMCBI
2010
176views more  BMCBI 2010»
14 years 9 months ago
Reverse engineering gene regulatory network from microarray data using linear time-variant model
nd: Gene regulatory network is an abstract mapping of gene regulations in living cells that can help to predict the system behavior of living organisms. Such prediction capability...
Mitra Kabir, Nasimul Noman, Hitoshi Iba
BMCBI
2008
155views more  BMCBI 2008»
14 years 9 months ago
Prediction of regulatory elements in mammalian genomes using chromatin signatures
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang
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BMCBI
2007
145views more  BMCBI 2007»
14 years 9 months ago
Improved benchmarks for computational motif discovery
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
Geir Kjetil Sandve, Osman Abul, Vegard Walseng, Fi...
BMCBI
2007
140views more  BMCBI 2007»
14 years 9 months ago
Accurate prediction of protein secondary structure and solvent accessibility by consensus combiners of sequence and structure in
Background: Structural properties of proteins such as secondary structure and solvent accessibility contribute to three-dimensional structure prediction, not only in the ab initio...
Gianluca Pollastri, Alberto J. M. Martin, Catherin...
BMCBI
2007
207views more  BMCBI 2007»
14 years 9 months ago
Analyzing in situ gene expression in the mouse brain with image registration, feature extraction and block clustering
Background: Many important high throughput projects use in situ hybridization and may require the analysis of images of spatial cross sections of organisms taken with cellular lev...
Manjunatha Jagalur, Chris Pal, Erik G. Learned-Mil...