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BMCBI
2010
109views more  BMCBI 2010»
15 years 6 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
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BMCBI
2010
156views more  BMCBI 2010»
15 years 6 months ago
Mathematical model for empirically optimizing large scale production of soluble protein domains
Background: Efficient dissection of large proteins into their structural domains is critical for high throughput proteome analysis. So far, no study has focused on mathematically ...
Eisuke Chikayama, Atsushi Kurotani, Takanori Tanak...
BMCBI
2010
103views more  BMCBI 2010»
15 years 6 months ago
MTRAP: Pairwise sequence alignment algorithm by a new measure based on transition probability between two consecutive pairs of r
Background: Sequence alignment is one of the most important techniques to analyze biological systems. It is also true that the alignment is not complete and we have to develop it ...
Toshihide Hara, Keiko Sato, Masanori Ohya
BMCBI
2010
193views more  BMCBI 2010»
15 years 6 months ago
caGrid Workflow Toolkit: A Taverna based workflow tool for cancer Grid
Background: In biological and medical domain, the use of web services made the data and computation functionality accessible in a unified manner, which helped automate the data pi...
Wei Tan, Ravi K. Madduri, Aleksandra Nenadic, Stia...
BMCBI
2007
94views more  BMCBI 2007»
15 years 6 months ago
Lightweight genome viewer: portable software for browsing genomics data in its chromosomal context
Background: Lightweight genome viewer (lwgv) is a web-based tool for visualization of sequence annotations in their chromosomal context. It performs most of the functions of large...
Jeremiah J. Faith, Andrew J. Olson, Timothy S. Gar...
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