Background: Mean-based clustering algorithms such as bisecting k-means generally lack robustness. Although componentwise median is a more robust alternative, it can be a poor cent...
Yuanyuan Ding, Xin Dang, Hanxiang Peng, Dawn Wilki...
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
In this paper, block diagonal linear discriminant analysis (BDLDA) is improved and applied to gene expression data. BDLDA is a classification tool with embedded feature selection...
Lingyan Sheng, Roger Pique-Regi, Shahab Asgharzade...
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
: Despite recent advances in DNA chip technology current microarray gene expression studies are still affected by high noise levels, small sample sizes and large numbers of uninfor...
Enrico Glaab, Jonathan M. Garibaldi, Natalio Krasn...