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68
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BMCBI
2010
88views more  BMCBI 2010»
14 years 10 months ago
Robust probabilistic superposition and comparison of protein structures
Background: Protein structure comparison is a central issue in structural bioinformatics. The standard dissimilarity measure for protein structures is the root mean square deviati...
Martin Mechelke, Michael Habeck
79
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ISMB
1997
14 years 11 months ago
Hierarchical Protein Structure Superposition Using Both Secondary Structure and Atomic Representations
The structural comparison of proteins has become increasingly important as a means to identify protein motifs and fold families. In this paper we present a new algorithm for the c...
Amit Pal Singh, Douglas L. Brutlag
99
Voted
JCB
2008
106views more  JCB 2008»
14 years 10 months ago
Statistics of Random Protein Superpositions: p-Values for Pairwise Structure Alignment
Quantification of statistical significance is essential for the interpretation of protein structural similarity. To address this, a random model for protein structure comparison w...
James O. Wrabl, Nick V. Grishin
73
Voted
JCC
2010
105views more  JCC 2010»
14 years 8 months ago
Fast determination of the optimal rotational matrix for macromolecular superpositions
: Finding the rotational matrix that minimizes the sum of squared deviations between two vectors is an important problem in bioinformatics and crystallography. Traditional algorith...
Pu Liu, Dimitris K. Agrafiotis, Douglas L. Theobal...
76
Voted
BMCBI
2008
124views more  BMCBI 2008»
14 years 10 months ago
Alignment of protein structures in the presence of domain motions
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...