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BMCBI
2008
110views more  BMCBI 2008»
14 years 11 months ago
Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
BMCBI
2006
150views more  BMCBI 2006»
14 years 11 months ago
Protein structure similarity from principle component correlation analysis
Background: Owing to rapid expansion of protein structure databases in recent years, methods of structure comparison are becoming increasingly effective and important in revealing...
Xiaobo Zhou, James Chou, Stephen T. C. Wong
BMCBI
2007
120views more  BMCBI 2007»
14 years 11 months ago
Non-coding sequence retrieval system for comparative genomic analysis of gene regulatory elements
Background: Completion of the human genome sequence along with other species allows for greater understanding of the biochemical mechanisms and processes that govern healthy as we...
Sung Tae Doh, Yunyu Zhang, Matthew H. Temple, Li C...
BMCBI
2004
128views more  BMCBI 2004»
14 years 11 months ago
Structural characterization of genomes by large scale sequence-structure threading: application of reliability analysis in struc
Background: We establish that the occurrence of protein folds among genomes can be accurately described with a Weibull function. Systems which exhibit Weibull character can be int...
Artem Cherkasov, Shannan J. Ho Sui, Robert C. Brun...
NAR
2011
331views Computer Vision» more  NAR 2011»
14 years 6 months ago
Community cyberinfrastructure for Advanced Microbial Ecology Research and Analysis: the CAMERA resource
The Community Cyberinfrastructure for Advanced Microbial Ecology Research and Analysis (CAMERA, http://camera.calit2.net/) is a database and associated computational infrastructur...
Shulei Sun, Jing Chen, Weizhong Li, Ilkay Altintas...