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» Roles in Information Systems: A Survey
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BMCBI
2005
132views more  BMCBI 2005»
15 years 1 months ago
CLPM: A Cross-Linked Peptide Mapping Algorithm for Mass Spectrometric Analysis
Background: Protein-protein, protein-DNA and protein-RNA interactions are of central importance in biological systems. Quadrapole Time-of-flight (Q-TOF) mass spectrometry is a sen...
Yong Tang, Yingfeng Chen, Cheryl F. Lichti, Roger ...
117
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BMCBI
2004
136views more  BMCBI 2004»
15 years 1 months ago
A SNP-centric database for the investigation of the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are an increasingly important tool for genetic and biomedical research. Although current genomic databases contain information o...
Alberto Riva, Isaac S. Kohane
132
Voted
BMCBI
2004
144views more  BMCBI 2004»
15 years 1 months ago
PASBio: predicate-argument structures for event extraction in molecular biology
Background: The exploitation of information extraction (IE), a technology aiming to provide instances of structured representations from free-form text, has been rapidly growing w...
Tuangthong Wattarujeekrit, Parantu K. Shah, Nigel ...
BMCBI
2002
126views more  BMCBI 2002»
15 years 1 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy
RE
2008
Springer
15 years 1 months ago
Design Science, Engineering Science and Requirements Engineering
For several decades there has been a debate in the computing sciences about the relative roles of design and empirical research, and about the contribution of design and research ...
Roel Wieringa, J. M. G. Heerkens