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BMCBI
2007
158views more  BMCBI 2007»
14 years 11 months ago
Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries
Background: The joint analysis of several categorical variables is a common task in many areas of biology, and is becoming central to systems biology investigations whose goal is ...
Corinne Dahinden, Giovanni Parmigiani, Mark C. Eme...
BMCBI
2010
146views more  BMCBI 2010»
14 years 11 months ago
Booly: a new data integration platform
Background: Data integration is an escalating problem in bioinformatics. We have developed a web tool and warehousing system, Booly, that features a simple yet flexible data model...
Long H. Do, Francisco F. Esteves, Harvey J. Karten...
BMCBI
2007
114views more  BMCBI 2007»
14 years 11 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...
BMCBI
2007
107views more  BMCBI 2007»
14 years 11 months ago
A general and efficient method for estimating continuous IBD functions for use in genome scans for QTL
Background: Identity by descent (IBD) matrix estimation is a central component in mapping of Quantitative Trait Loci (QTL) using variance component models. A large number of algor...
Francois Besnier, Örjan Carlborg
BMCBI
2008
164views more  BMCBI 2008»
14 years 11 months ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke