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» SIMAGE: simulation of DNA-microarray gene expression data
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AAAI
2008
15 years 1 months ago
Generating Application-Specific Benchmark Models for Complex Systems
Automated generators for synthetic models and data can play a crucial role in designing new algorithms/modelframeworks, given the sparsity of benchmark models for empirical analys...
Jun Wang, Gregory M. Provan
BMCBI
2010
98views more  BMCBI 2010»
14 years 11 months ago
A semi-nonparametric mixture model for selecting functionally consistent proteins
Background: High-throughput technologies have led to a new era of proteomics. Although protein microarray experiments are becoming more common place there are a variety of experim...
Lianbo Yu, R. W. Doerge
BMCBI
2008
159views more  BMCBI 2008»
14 years 11 months ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin
BMCBI
2010
102views more  BMCBI 2010»
14 years 11 months ago
Quantized correlation coefficient for measuring reproducibility of ChIP-chip data
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
Shouyong Peng, Mitzi I. Kuroda, Peter J. Park
BMCBI
2008
126views more  BMCBI 2008»
14 years 11 months ago
NITPICK: peak identification for mass spectrometry data
Background: The reliable extraction of features from mass spectra is a fundamental step in the automated analysis of proteomic mass spectrometry (MS) experiments. Results: This co...
Bernhard Y. Renard, Marc Kirchner, Hanno Steen, Ju...