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» SNAPper: gene order predicts gene function
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BMCBI
2007
148views more  BMCBI 2007»
14 years 12 months ago
p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data
Background: The p53 gene family consists of the three genes p53, p63 and p73, which have polyhedral non-overlapping functions in pivotal cellular processes such as DNA synthesis a...
Elisabetta Sbisà, Domenico Catalano, Giorgi...
NAR
2008
103views more  NAR 2008»
14 years 11 months ago
DBD--taxonomically broad transcription factor predictions: new content and functionality
DNA-binding domain (DBD) is a database of predicted sequence-specific DNA-binding transcription factors (TFs) for all publicly available proteomes. The proteomes have increased fr...
Derek Wilson, Varodom Charoensawan, Sarah K. Kumme...
RECOMB
2003
Springer
16 years 4 days ago
Whole-genome comparative annotation and regulatory motif discovery in multiple yeast species
In [13] we reported the genome sequences of S. paradoxus, S. mikatae and S. bayanus and compared these three yeast species to their close relative, S. cerevisiae. Genome-wide comp...
Manolis Kamvysselis, Nick Patterson, Bruce Birren,...
BMCBI
2010
160views more  BMCBI 2010»
14 years 12 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BMCBI
2008
82views more  BMCBI 2008»
14 years 12 months ago
Studying the functional conservation of cis-regulatory modules and their transcriptional output
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...
Denis C. Bauer, Timothy L. Bailey